44 Posts

jaxlab #Repost @brainsurgerydropout, who we always appreciate for his great #neuroscience posts!
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🔬 The beautiful capillary network of the #brain (#cerebralcortex) as seen with #multiphoton #microscopy. The image is a pseudo colored depth projection based on #ROYGBIV (RED is deep, VIOLET is more superficial). You can even see single blood cells trafficking in the vessels as black stripes. Typically, the more distinct the stripes are and the wider they are spaced out, the slower the velocity of the blood in the vessel segment. Now imagine a future where the #neurosurgeon has this virtual view superimposed on the living brain during #surgery.... #oculusvr #biophysics #vascularbiology #neuroscience #microscope #cancer #glioblastoma #metastasis #neurosurgery #CNS #medicine #neurology #anatomy #leica #biotechnology #startup #biotechstartup
4w

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Clarendon Spectra-Physics
spectraphysics See our new bio-imaging video #multiphoton http://ow.ly/10gVBr 1mon

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olympuslifescience The amount of complexity found within the brain never ceases to amaze. This image shows the hippocampus of a mouse, an area that is thought to play a role in memory and spatial navigation.

Credit: Thomas Deerinck

#olympus #bioscapes #sciart #multiphoton #microscopy #microscope #micro #microscopic #microscopes #nature #science #research #optics #imaging #objective #braincell #brain #neuroscience #neuron #cell #cells #photooftheday #photomicrograph #🔬
1mon

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leica.microsystems Observe the development of a zebrafish (danio rerio) embryo recorded with multiphoton microscopy over 21 hours in quick motion.
Using the long wavelength light of an infrared laser as illumination source enables recording a living organism over a long period of time without damaging the specimen and to have a deep look into it. More details about multiphoton microscopy can be found at http://goo.gl/n2b3qt Courtesy: Nadine Peyriéras, BioEmergences USR3695 (IBiSA FBI), Gif sur Yvettes, France #fromeyetoinsight #leicamicrosystems #microscope #multiphoton #microscopy #zebrafish #daniorerio #embryo #development #timelapse #science #artscience #microscopy
2mon

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brainsurgerydropout #🔬 The beautiful capillary network of the #brain (#cerebralcortex) as seen with #multiphoton #microscopy. The image is a pseudo colored depth projection based on -- this should get the #premed folks excited -- #ROYGBIV (RED is deep, VIOLET is more superficial). You can even see single blood cells trafficking in the vessels as black stripes. Typically, the more distinct the stripes are and the wider they are spaced out, the slower the velocity of the blood in the vessel segment. Now imagine a future where the #neurosurgeon has this virtual view superimposed on the living brain during #surgery.... #oculusvr #biophysics #vascularbiology #neuroscience #microscope #cancer #glioblastoma #metastasis #neurosurgery #CNS #medicine #neurology #anatomy #leica #biotechnology #startup #biotechstartup 2mon

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Hefe Startup Founder & Cancer KILLA

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brainsurgerydropout #BrainMetastasis This is a composite image of a #brain section with multiple #metastatic #breastcancer colonies (green; blood vessels are red). You can see distinct patterns of growth because cancer is heterogeneous (made up of genetically-distinct cells). My first #postdoc work identified the receptor metastatic cancer cells use to establish and grow in the brain. It turns out this receptor is critical for growth and progression of many aggressive solid cancers including #glioblastoma. This is the receptor we are now targeting with our first drug candidate... We feel it will be a game changer. @fashionsurgeon and I are working hard to bring this to #clinicaltrials! 🔬 PS: the scale bar is 1mm. #science #microscopy #leica #confocal #multiphoton #immunohistochemistry #gfp #neurosurgery #surgery #medschool #premed #laboratory #oncology #breastcancer #orphandrug #biotechnology #startup #startuplife #startupgrind 6mon

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Normal Spectra-Physics
spectraphysics New Image Gallery for #multiphoton multimodal bio-imaging: DM us to contribute your images http://ow.ly/SlLpF 8mon

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olympuslifescience The labeling technique presented here has the playful name, "brainbow." Using this process, individual brain neurons are labeled with different colors, allowing researchers to easily distinguish them from one another.

Credit: Pierre Mahou

#olympus #bioscapes #multiphoton #3D #video #neuron #bioscience #biology #bird #birds #brainbow #neurology #neuroscience #neurons #microscopy #microscope #microscopic #micro #microscopes #nature #science #research #optics #imaging #objective #cell #cells #🔬
9mon

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brainsurgerydropout #Timelapse imaging of active blood flow in #brain capillaries of the cortex imaged with #multiphoton #microscopy. The blood was imaged with intravascular dye therefore the black voids and streaks represent shadows of single red blood cells trafficking through the capillaries. These shadows can be used to calculate velocity in individual capillary segments with calculus (see, it is useful for something! ). Images are taken 1 second apart. #vascularbiology #neuroscience #neurosurgery #laboratory #microscopy #medicine #science #cancer #research #biophysics #biotechnology #startup 9mon
  •   brainsurgerydropout @7th_individuality It wasn't actually a "dye" per se... we used a FITC-dextran with high enough molecular weight that it stays in the intravascular compartment for several hours. Great question. 8mon
  •   7th_individuality Thanks for your prompt response. I didn't know about FITC-dextran staying in for long hours. What is that you're working on? This is so cool by the way. Do you use any neuroscience computations? 8mon
  •   brainsurgerydropout @7th_individuality This was from my first postdoc actually. We were looking to study single cell metastasis in the brain. While generally proficient at maths, I usually outsource it. 8mon
  •   7th_individuality Awesome. 8mon

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brainsurgerydropout #FGF One of my favorite images from #Oxford where I spent 50% of my life in the dark of the microscope room. I spent so much time in there the only other country I visited in 3 years was Ireland, haha. #ScienceWins This is a 2D depth projection image of a growing triple negative #BreastCancer #metastasis in the brain... violet cells are towards the top of the pile, red at the bottom. #fuckglioblastomafriday #fuckcancer #cancerresearch #medicine #laboratory #science #oncology #multiphoton #microscopy #brainbow #neuroscience #startup #sciart #biotechnology 9mon

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olympuslifescience This capture shows immune cells in action, actively defending a mouse against infection. This sample was created using intravital #microscopy.

Credit: Dr. Thorsten Mempel
#multiphoton #olympus #bioscapes #fluorescent #fluorescence #color #colorful #cells #cellbiology #biology #rodent #science #research #pathology #intravital #video #mouse #optics #objective #micro #microscopic #microscopy #microscopes #🔬
10mon

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Normal Spectra-Physics
spectraphysics New article: Compact fixed wavelength #femtosecond #Lasers for #Multiphoton #Imaging #SPIE http://ow.ly/NWdqn 11mon

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Normal Spectra-Physics
spectraphysics New article:#Multiphoton #Imaging w/high-peak-power #Laser -- see more@LASER_Munich A2.307 ow.ly/NWcwD 12mon

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