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pippashappinessproject #beach vibes; I had a bit too much sun today. Still learning to find balance, I play too hard and pay later. When we live with chronic illness we watch life move by and when we step on the carousel it's hard to step back off and leave the fun behind. This is the balance I still need to learn. #rheumatoidarthritis #lupus #fibromyalgia #chronicpain #chronicillness #hope #inspiration #spoonie #autoimmunedisease #JRA #Invisibledisability #anxiety #rawarrior #payitforward #randomactsofkindness  #CFS #chemo  #IBS #Methotrexate #orencia #cimzia #PippasHappinessProject #kindnessmatters  #begoodtopeople #mindfulliving 1d

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vongraves (If you know me, you know how much fun I've had tonight researching this for a few hours. ) Biologics/biotherapies are not grouped together with chemotherapy because they are more targeted drugs and are actually proteins as opposed to chemicals that take aim at other proteins found on cancer/rapidly growing cells. Biologics can target the cancer in a specific way and may work synergistically with chemotherapy, but are not actually chemotherapy. The two are often grouped under the same umbrella because of their ability to work so close together. According to many of the articles I've read, the future of cancer treatment looks to be heading towards using biotherapy as opposed to chemotherapy. The biotherapies that are being/will be used in the treatment of cancer are not the same ones used to treat many autoimmune diseases/disorders today. Some that are being used are:

Aldesleukin (Proleukin)
G-CSF (Neupogen)
GM-CSF (Leukine, Prokine)
Erythropoietin (Procrit, Epogen)
Oprelvekin (Neumega)
Interferon alpha 2a (Roferon A)
Interferon beta-1a ( Avonex , Rebif )
Interferon beta-1b (eg, Betaseron)
Interferon gamma-1b ( Actimmune), (The following are monoclonal antibodies more commonly used in cancer treatment currently. These are in the same family as Remicade, Humira, Cimzia, Stelara, Tysabri, & Entyvio.) Rituximab (Rituxan)
Trastuzumab (Herceptin)
Cetuximab (Erbitux)
Panitumumab (Vectibix)
Bevacizumab (Avastin)
Alemtuzumab (Campath)
Ipilimumab (Yervoy)

While these are being used in the treatment of cancer, they are biologics & do not work in the body the same way as chemotherapy nor are they structurally similar. Biotherapy & chemotherapy are not the same thing.
Note: Remicade is debated on which it falls under. Seeing as how it has the biological component, a chimeric monoclonal antibody, it is a biologic therapy. However in billing, it is billed as chemotherapy whereas the rest are not.
1d
  •   blairmckinney For some reason my body absolutely hates any biologic they've tried. Within 1-3 months of starting any of them I have sky high levels of antibodies 1d
  •   vongraves @blairmckinney My body is the same exact way. You're putting "humanized" mice proteins in your body. Yes, they're humanized, but they're still foreign proteins. It's similar to your body rejecting an organ. It's not yours naturally so your body rejects it. 1d
  •   blairmckinney Yes I mean Crohns is the definition of attacking itself so of course it's most likely going to attack an actual "foreign" product. 1d
  •   amy_lou19 It's nothing like rejecting an organ...sorry. It may be in the similar in 'antibody' terms but comparing a biological that 'stops working' and an transplanted organ being 'rejected'! Very different outcomes. 1d
  •   vongraves @amy_lou19 It's not just that the drug stops working. Your body developed antibodies for it & literally attacks it. I've had an anaphylactic reaction to one of these...twice... & nearly needed to be intubated. It's the same basic principle. Your body recognizes a foreign "invader" & attacks it. You're more likely to die from an organ transplant rejection, but it can happen in anaphylactic cases as well. That wasn't the point. The point was that it's a similar scenario happening within the body. 18h
  •   amy_lou19 Sorry if it's coming across as a bit arggggh I don't mean it that way and get what you are trying to say. Just hope you realise what I'm trying to imply too. That in paper it may look a perfect analysis but in reality it is very different. 16h
  •   vongraves @amy_lou19 It's an analogy for how the body reacts to a foreign invader. The actual symptoms that come with each are vastly different. I am aware of this, but for some it's easier to understand in that way. I am sorry if I've offended you. I just can't exactly start using medical jargon & scientific explanations & expect people to understand that. I definitely get what you're saying. I'm not trying to belittle what you've been through. 15h
  •   amy_lou19 No it's fine. I guessed that's what you were saying. I guess im just a bit twitchy on the subject cause two friends of mine are going through bad rejection at the min one of which is on his second set of organs and who has rejected then again. We have our antibodies checked a lot so if any issues they would be addressed, if only it was as simple but its unfortunately not hey. X 14h

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vongraves Tonight I'm doing some research on the difference between chemotherapy & biologics/biotherapy. While I continue reading, here's a cool chart to know where the antibodies in your biologics come from. 🏻 #crohns #crohnsdisease #crohnie #ibd #inflammatoryboweldisease #nocolonstillrollin #gotguts #ostomy #ostomate #ileostomy #spoonie #cimzia #remicade #entyvio #humira #stelara #tysabri #biologics #biologictherapy #medicine #treatment #science #antibodies 1d

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pippashappinessproject The #sunset from last night's #beach stroll. A little bit of #peace for my #spooniefamily I love to see other people's #travel photos on the days when I am very unwell and and am unable to make it out of the house. I hope you enjoy mine as well. Love and hugs from #Pippa #rheumatoidarthritis #lupus #fibromyalgia #chronicpain #chronicillness #hope #inspiration #spoonie #autoimmunedisease #JRA #Invisibledisability #anxiety #rawarrior #chrons  #payitforward #randomactsofkindness  #CFS #chemo  #orencia #cimzia #PippasHappinessProject #kindnessmatters  #begoodtopeople #mindfulliving 2d

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lunettezz #spoonieadvice needed pretty please. I'm trying to book flights to see this, but it looks like I'm gonna have to travel with my injections. My rheumy gave me a note for flying and I also got a little cooling bag for it, but I'm still wondering if airport/airplane staff know how to handle meds? Any feedback will be greatly appreciated 2d

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a.s.warrior It's crazy to think of what I'm injecting into my body. The benefits out weight the side effects since I'm able to actually function since starting Cimzia but being on this for the rest of my life is extremely scary. My chances of getting cancer, especially lymphoma are three times that of a normal person and double the chance of contracting infections in general. Infertility is also an issue along with shorter life span. It's all a lot to take in and I'm just grateful that it's not worse. If you are in good health, count your blessings & take care of yourself! Eat healthy, exercise and be sure to get check ups and exams according to your age and gender.
#autoimmunedisease
#ankylosingspondylitis
#cimzia
#chemo
#spoonie
#invisableillness
#FightBack
#scarednotgonnalie
#grateful
#couldbeworse
#healthychoices
#nutrition
#lynphoma
3d
  •   loren_hall Hello there! Please check out my last post as we have created a social media app for those with disabilities and more to share their journey with others! Please help us spread the word! 3d
  •   a.s.warrior @mixedbatman I couldn't find it :( 3d

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nirvana48 2015年07月24日
23回目のシムジアを注射

#膠原病 #リウマチ #注射
#生物学的製剤 #シムジア
#rheumatoidarthritis #rheumatism
#cimzia
効いて欲しい
MMP-3 384 基準値は60
この2年半、かなり数値が高い
焦っちゃ駄目と思いつつも焦る
4d
  •   mahinapiha 数値安定しますように 3d
  •   manamana1211 数値高くて体はしんどくないですか?大丈夫です(;´Д`A 早く効くといいですが… 3d
  •   yappi0326 安定しないと焦りますよね。早くききますように! 3d
  •   nirvana48 @mahinapiha ありがとうございます励ましてもらえて嬉しいです 3d
  •   nirvana48 @manamana1211 数ヶ月前までかなりしんどかったんですけど、ここ1ヶ月は何故か体が軽く感じますもっとシムジアが、ガツン!!と効いてもらいたいものです頑張れシムジア!と念じながら注射してます(笑) 3d
  •   nirvana48 @yappi0326 ありがとうございます ついつい焦っちゃうんですよ落ち着かなくちゃ 3d

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  •   twiginpink Hey cutie! Have fun! 4d
  •   serenedevices Outstanding! 3d
  •   myspoonsandme Pippa! You are just gorgeous! I hope that you are having fun and are able to enjoy yourself and not over extend yourself!!! Blessings, sweet one!! 2d
  •   tumble_queen_1 It's a t- Rex! Haha 11h

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pippashappinessproject @jennyleigh426 Here is your care package @begoodtopeople @handi-pin I hope it puts a smile on your face and lifts your spirits. There is a journal, a purse size mirror, 2 necklaces, some hair bands, colored pens, #begoodtopeople swag and the #handipin is great to wear when you have invisible disabilities.
This project of giving continues, due to the generous donations of others #rheumatoidarthritis #lupus #fibromyalgia #chronicpain #chronicillness #hope #inspiration #spoonie #autoimmunedisease #JRA #Invisibledisability #anxiety #rawarrior #chrons  #payitforward #randomactsofkindness  #CFS #chemo  #IBS #Methotrexate #orencia #cimzia #PippasHappinessProject #kindnessmatters  #begoodtopeople #mindfulliving #handipin #thehappinessplanner
4d
  •   collective_sunshine You are awesome and these are so great 4d
  •   pippashappinessproject @nickcannon was on the @dr_oz today and let the world know he has Lupus. I am very sorry he has an autoimmune disease but I am so grateful that he spoke about it today. At times, I feel my voice is so small but, when someone who has media power such as Nick, it inspires me!!! I feel that one day my goal will be reached. My mission is for all people on earth to have a basic idea of what an autoimmune disease is, I want people to understand, that for us, there is no cure. My hope is that our voices will be heard and that medical science will keep researching to find a cure #fightingtostayalive 4d
  •   jennyleigh426 Thank you so much!!! I cannot wait to receive this blessing in the post!! It will definitely keep my spirits up and help me through this rough bit that I'm going through. Once again, you're an angel. Bless you!!! 4d
  •   kimmie.kat I do intend on giving donations I just haven't been feeling well lately, & Got notice that I have to move very soon. When things calm down I will send some things xo 4d
  •   pippashappinessproject @kimmie.kat awe, thank you very much! 4d
  •   begoodtopeople You are so incredible @pippashappinessproject and so is your community. 4d

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lunettezz Coffee, dots, Grey's Anatomy, and a lovely thunderstorm... No need to water the garden, yay! 5d

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  •   bec_d808 No experience but hoping to be in the same situation one day! 5d
  •   hla_b27 It's possible somebody's got to have done it 5d
  •   madge_hiphop Your IG is super! You should visit my profile 3d
  •   lorparks @hla_b27 @bec_d808 hey guys, I travelled for 7 weeks with humira. Depsite what they tell you about ther urgency of it being in the fridge its okay for about a month out and then I just pushed it a little longer with the last. The medicine builds up in your system so I thought even if it was less effective it was better then nothing right. Some airlines if you speak to them prior will refrigerate the needles for you and if you are staying in places with fridges if you can keep it in an insulated bag moving it from fridge to fridge will be fine. As i travelled through a lot of different countries fast and stayed in hostels I didnt have access to this. I just kept it in a insulated bag, crossed my fingers and I was fine. If you have any more questions happy to answer. I do have more info about my condition ect on my insta @parker29 10h
  •   hla_b27 Thank you @lorparks 😀 59min
  •   lorparks Most welcome. Hope it all works out for you x 34min

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_kboo_ Trying out #Enbrel for my #RheumatoidArthritis hoping for a miracle. With all the medications I'm on I shouldn't be in this much pain, nothing seems to be working for me #Cimzia just wasn't cutting it for me anymore. So now I have to self inject this little gem once a week had 10 tubes of blood drawn today too.. Oh the fun adventures of being a chronic pain warrior! #RA #RheumatoidArthritis #Enbrel #Fibromyalgia #ChronicPain #StayPositive #BeStrong #PrayersNeeded #ChronicPainWarrior 5d
  •   forgetmenot_priya Stay strong hun. I completely understand what you're going through. Last week I had 11vials of blood drawn because Drs weren't sure why I was having an allergic reaction to cimzia when all the results were negative. I hope Enbrel works for you. Sending gently hugs your way 5d

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lunettezz Heatwave my ass! Been going sockless for two days, and now I've got a cold! The socks are back on, bring on the 37°C, I'm ready! 6d

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